This PhD project offers an exciting opportunity to explore the intersection of nutrition, immunity, and microbiology. By investigating how polyphenols, a class of bioactive dietary compounds, interact with the gut microbiota, this research seeks to shed light on their potential role in modulating mucosal immune function.
The project will focus on understanding the mechanisms through which polyphenols are metabolized by gut bacteria to produce bioactive metabolites that may have beneficial effects on the immune system. Using state-of-the-art tools like molecular microbiology, transcriptomics, and gene editing, the student will investigate the metabolic pathways involved in polyphenol degradation. The research will extend into practical applications by assessing whether a synbiotic approach—combining polyphenols and specific bacteria—can enhance mucosal immunity in models of bacterial and parasitic infections.
As part of an interdisciplinary collaboration, the PhD student will work alongside the Phage and Quorum Sensing group, under the guidance of Associate Professor Nina Molin Høyland-Kroghsbo. The project will also offer international exposure through a stay at the University of California, Davis, allowing the student to gain further insights into cutting-edge research in this field.
Beyond research, the student will have opportunities to contribute to teaching, which will enrich their academic experience.
This project is a unique opportunity for anyone passionate about molecular immunology, microbiome research, and the potential of dietary components in promoting health. Full training will be provided to equip the student with the necessary skills to succeed in this multi-faceted research environment.
Application deadline: 26-01-2025